Feline infectious peritonitis epizootic caused by a recombinant coronavirus.

ABSTRACT: Cross-species transmission of coronaviruses (CoVs) poses a serious threat to both animal and human health^1-3. While the large RNA genome of CoVs shows relatively low mutation rates, recombination within genera is frequently observed^4-7. Companion animals are often overlooked in the transmission cycle of viral diseases; however, the close relationship of feline (FCoV) and canine CoV (CCoV) to human hCoV-229E^5,8, as well as the susceptibility of these animals to SARS-CoV-2⁹, highlight their importance in potential transmission cycles. While recombination between CCoV and FCoV of a large fragment spanning orf1b to M has been previously described^5,10, here we report the emergence of a highly pathogenic FCoV-CCoV recombinant responsible for

SUBMITTER: Attipa C 

PROVIDER: S-EPMC12408369 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature