Long-term cardiovascular outcomes and mortality following Kawasaki disease: A systematic review and meta-analysis.

ABSTRACT:

Objectives

To determine if children with Kawasaki disease (KD) are at an increased long-term risk of cardiovascular disease and mortality.

Methods

A systematic review and meta-analysis was performed. A systematic search of MEDLINE, EMBASE, CINAHL, Cochrane, and Web of Science databases was performed through 2022. English-language publications, patients 0 to 18 years at KD diagnosis, minimum follow-up >1 year, and ≥10 patients included. Of 5072 articles, 181 were included. Cardiovascular events and mortality were extracted and pooled for analysis. Meta-analyses and meta-regression analyses were performed. The primary outcome of interest was the incidence of specific cardiovascular events (composite of myocardial infarction, heart failure or cardiac arrest) and all-cause morta

SUBMITTER: Lao F 

PROVIDER: S-EPMC12408477 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature