Retinal Layer Thickness and Volume Measurements in Traumatic Brain Injury.

ABSTRACT: Purpose: To assess retinal layer thickness and volume by optical coherence tomography (OCT) in patients with prior traumatic brain injury (TBI). Methods: Adults (≥18 years) with prior TBI were prospectively recruited. 512 × 128-mm macular cube scans were obtained using Zeiss Cirrus HD-5000 OCT. The previously validated Duke Reading Center's DRCVisualizer semiautomatically segmented (manually corrected) the ganglion cell-inner plexiform (GC-IPL), inner nuclear (INL), outer plexiform (OPL), outer nuclear (ONL), photoreceptors (PR), and retinal pigment epithelium (RPE) layers. Mean thickness and volume were obtained within 3- and 6-mm ETDRS perifoveal rings. Individuals were age- and sex-matched (±5 years) with controls. Results: Thirty-eight patients with TBI (66 eyes; m

SUBMITTER: Karthik N 

PROVIDER: S-EPMC12408546 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature