Natural progression and prediction markers in non-clinically significant oesophageal varices in children.

ABSTRACT:

Objectives

Limited literature exists on non-clinically significant varices (nCSV) and progression in children with portal hypertension (PHT). This study investigates trends and associations in this cohort.

Methods

This retrospective cohort study analysed 70 children with nCSV undergoing surveillance endoscopy between January 2012 and 2024. Laboratory parameters, prediction scores and fibroscan results were collected. Statistical analysis include Mann-Whitney U test, chi-squared test and receiver operating characteristic.

Results

Ten children (14.3%) presented with portal vein thrombosis (PVT), 26 (37.1%) with non-biliary atresia chronic liver disease (CLD) and 34 (48.6%) with biliary atresia (BA). Twenty-five children (35.7%) had variceal progression, with median year

SUBMITTER: Chan C 

PROVIDER: S-EPMC12408977 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature