Joint effects of prognostic nutritional index and skeletal muscle index on prognosis of decompensated cirrhosis: a retrospective cohort study.

ABSTRACT:

Background

Liver cirrhosis, characterized by chronic inflammation, is frequently complicated by malnutrition. Nutritional indices, such as the prognostic nutritional index (PNI) and the skeletal muscle index (SMI), calculated as the muscle area quantified via CT scans at the third lumbar vertebra level divided by the square of the patient's height in meters (cm²/m²), are associated with outcomes in inflammatory diseases.

Objectives

We aimed to evaluate the diagnostic efficacy of the PNI both independently and in combination with the SMI for identifying malnutrition in cirrhosis and to explore their prognostic implications.

Design

A single-center retrospective cohort study of 262 hospitalized cirrhotic patients (2018-2023). Malnutrition was assess

SUBMITTER: Yao S 

PROVIDER: S-EPMC12409061 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature