Finite element and preclinical analysis of tissue response to negative pressure wound therapy with a felted foam containing 10 mm through holes.

ABSTRACT:

Introduction

Not all wound patients are candidates for surgical debridement. A felted, reticulated open cell foam with an array of 10 mm holes (VFCC) for use with instillation therapy has been used to eliminate non-viable tissue from patient wound beds. The mechanisms for this have not been fully elucidated. The current study elaborates the biomechanical stresses, strains and work imparted to tissue with VFCC versus commonly used reticulated open cell foam (ROCF) dressings.

Methods

Finite element analysis (FEA) measured strain and deformation occurring at the tissue interface with VFCC or ROCF. FEA results were compared to those in a preclinical, porcine sloughy wound model.

Results

The peak maximum principal strain imparted to tissue at -125 mmHg with VFCC was 27.8%

SUBMITTER: McNulty AK 

PROVIDER: S-EPMC12409140 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature