Changes in adiposity indices over 10 years and risk of type 2 diabetes: The Whitehall II cohort study.

ABSTRACT:

Aims

Common adiposity indices that are used to assess obesity include body mass index (BMI), waist circumference (WC) and waist-to-height ratio (WHtR). We aim to investigate change rates of the three indices in British middle-aged adults and compare effects of different adiposity indices' changes on incident type 2 diabetes.

Materials and methods

Three repeated measures of BMI, WC and WHtR were collected over a decade (1991-2004) in 5666 participants without diabetes from the Whitehall II cohort study of British civil servants. Linear mixed-effects models were used to estimate standardised individual change rates of the three indices, and participants were then followed up for incident diabetes until 2023. We examined the prospective associations between change rates of the

SUBMITTER: Huang C 

PROVIDER: S-EPMC12409207 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature