Associations of adverse childhood experiences with midlife cardiovascular health in women.

ABSTRACT:

Background

Cardiovascular health (CVH) may be influenced by early life factors, such as adverse childhood experiences (ACEs). Prior work suggests social stressors may particularly influence CVH trajectories across the lifecourse in women; however, this relationship remains poorly understood. We used data from a prospective longitudinal cohort study to evaluate associations of ACEs with CVH and its components among midlife women (mean 51.3y).

Methods

We included 588 women from Project Viva who delivered a singleton livebirth between 1999 and 2003. The primary exposure was number of ACEs experienced (continuous and by domain) and the primary outcome was Life's Essential 8 (LE8) CVH score, an average of eight behavioral and biomedical factors (0-100 points, higher score = bette

SUBMITTER: Wang G 

PROVIDER: S-EPMC12409455 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature