<i>Staphylococcus aureus</i> Adhesion on Hydrophobin Coatings: Adhesion Forces and the Influence of Surface Charge.

ABSTRACT: Staphylococcus aureus (S. aureus) is one of the bacterial species capable of forming multilayered biofilms on implants. Such biofilms formed on implanted medical devices often require the removal of the implant in order to avoid sepsis or, in the worst case, even the death of the patient. To address the problem of unwanted S. aureus biofilm formation, its first step, i.e., adhesion, must be understood and prevented. Thus, the development of adhesion-reducing surface coatings for implant materials is of utmost importance. In this work, we used single-cell force spectroscopy to analyze the adhesion of the biofilm-forming S. aureus strain SA113 on naive and protein-coated silicon surfaces (SiO₂). In addition to the wild type, we used the SA113 ΔdltA</

SUBMITTER: Nolle F 

PROVIDER: S-EPMC12409555 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature