Challenges in using massively parallel sequencing technology for forensic DNA analysis in Southeast Asia.

ABSTRACT: Massively parallel sequencing (MPS) has caused a paradigm shift in forensic DNA analysis by enabling simultaneous examination of multiple genetic markers with higher resolution. Despite its growing importance, adoption in the 11 Southeast Asian countries remains limited. This paper reviews MPS implementation in forensic DNA laboratories across the region and discusses key adoption challenges. An online survey with the Asian Forensic Sciences Network - DNA Workgroup (AFSN-DNAWG) received 19 responses from seven countries: Brunei Darussalam, Indonesia, Malaysia, the Philippines, Singapore, Thailand, and Vietnam. Eight respondents are using MPS, while 10 of 11 non-users plan to adopt it within five years. Key challenges for users included limited population data, lack of standardized internat

SUBMITTER: Estrella CS 

PROVIDER: S-EPMC12409974 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature