Development of Dual-Functional Titanium Implant for Osseointegration and Antimicrobial Effects via Plasma Modification.

ABSTRACT:

Introduction and aims

Titanium dental implants are widely used in clinical practice; however, they still face challenges such as implant loosening and infection. Recent studies focus on improving integration and infection resistance. In this study, a low-temperature plasma treatment was employed to fabricate a dual-functional modification layer on the titanium implant surface, offering a promising strategy that simultaneously promoted bone integration and effectively inhibited bacterial infection.

Materials and methods

This was achieved by depositing a hexamethyldisilazane (HMDSZ) film on the surface of titanium implants and grafting a thermosensitive composite hydrogel designed as a drug delivery system. The natural cross-linker genipin was used to immobilize chlorhexidine

SUBMITTER: Chuang TL 

PROVIDER: S-EPMC12410398 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature