Diagnostic performance of the Hightop Rapid Diagnostic Test for the detection of anti<b>-</b> <i>Treponema pallidum</i> antibodies in Cameroon: a laboratory-based cross-sectional and comparative study.

ABSTRACT:

Objective

The study was conducted to assess the diagnostic performance of the Hightop Syphilis Rapid Diagnostic Test (RDT) in comparison with the ELISA test used as a reference method.

Design

A laboratory-based cross-sectional and comparative study was conducted to assess the diagnostic performance of the Hightop Syphilis RDT.

Setting

Blood samples obtained from adult participants in eight health facilities were analysed at the National Public Health Laboratory (NPHL), Ministry of Public Health, Yaounde, Cameroon.

Participants

From 29 April to 25 August 2023, 583 adult participants of both sexes (aged ≥21 years), including both syphilis positive and syphilis negative, were recruited consecutively in eight health facilities in eight regions of Cameroon.

Outco

SUBMITTER: Taheu Ngounouh C 

PROVIDER: S-EPMC12410608 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature