Impact of bronchitis variability on outcomes of COPD.

ABSTRACT:

Objective

This study aimed to evaluate the impact of serial bronchitic status over two consecutive years on clinical outcomes, including frequency of exacerbation and lung function decline rate.

Methods

We analysed data from 1265 participants enrolled in the Korea COPD Subgroup Study, a nationwide prospective observational chronic obstructive pulmonary disease (COPD) cohort. Bronchitic status was determined using subquestionnaires of the COPD Assessment Test at baseline and after 1 year, classifying patients into three serial bronchitic groups of persistently not bronchitic (NB), intermittently bronchitic (IB) and chronic bronchitis (CB). Annualised exacerbation rates and longitudinal lung function decline rates were analysed.

Results

The NB group consisted of 873 ind

SUBMITTER: Choi JY 

PROVIDER: S-EPMC12410636 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature