Breast cancer classification based on the integration of diagnostic algorithms for calcifications and masses using a mixture of experts.

ABSTRACT:

Purpose

To investigate the effectiveness of an integrated deep-learning (DL) algorithm, the Mixture of Radiological Findings Specific Experts (MoRFSE), in breast cancer classification by imitating the diagnostic decision-making process of radiologists.

Methods

A total of 2,764 mammographic images (1,462 breast cancer, 248 benign lesions, and 1,054 normal breast tissue) from the TOMPEI-CMMD were used. The MoRFSE comprises three DL models: a gate network for categorization (gNet) and two classification expert networks (cExp and mExp) specialized in capturing the distinct characteristics of calcifications and masses, respectively. This structure imitates radiologists' comprehensive diagnostic process by applying distinct algorithms for different lesion types. The classification

SUBMITTER: Konaka Y 

PROVIDER: S-EPMC12410704 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature