A novel automated CT biomarker to predict outcomes in acute ischemic stroke: net water uptake.

ABSTRACT:

Background

Recent trials of large core thrombectomy have shown that our traditional understanding of infarct characteristics and reperfusion benefit may be incomplete for patients with acute ischemic stroke (AIS). The Alberta Stroke Program Early CT Score (ASPECTS) has wide inter-rater variability, and modern studies have also shown that reperfusion therapies can benefit some patients regardless of the ASPECTS. Reproducible imaging metrics that account for the degree of hypo-attenuation on non-contrast computed tomography (NCCT) may be better suited to guide treatments. Here, we evaluate Net Water Uptake (NWU), a novel NCCT metric that can be calculated in a rapid and automated fashion, to determine its predictive performance for identifying clinical outcomes in patients with AIS c

SUBMITTER: Mallavarapu M 

PROVIDER: S-EPMC12411213 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature