The global, regional, and national impact of laryngeal cancer from 1990 to 2021, along with forecasts for 2050: a comprehensive analysis for the Global Burden of Disease 2021 research.

ABSTRACT:

Background

Laryngeal cancer (LC), the second most common head and neck malignancy, with significant global geographical disparities in incidence and mortality, was analyzed using 2021 Global Burden of Disease (GBD) data to assess Socio-Demographic Index (SDI) correlations and project disease burden through 2050, aiming to reduce its global impact.

Methods

Using data from the GBD 2021, we investigated the incidence, prevalence, deaths, and Disability-Adjusted Life Years (DALYs) of LC, as well as trends, age-sex-time patterns, driving factors, and projections up to 2050.

Results

In 2021, LC increased with age and decreased after the age of 70. The incidence and mortality rates of male patients are much higher than those of female patients, and the gap between men and wo

SUBMITTER: Duan T 

PROVIDER: S-EPMC12411215 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature