Association of whole blood essential metals with neurodevelopment among preschool children.

ABSTRACT:

Background

Essential metals may play roles in neurodevelopment. The aim was to evaluate the associations of magnesium (Mg), iron (Fe), copper (Cu), and zinc (Zn) levels with neurodevelopment among preschool children.

Methods

The medical records of eligible children enrolled between January 2019 and July 2022 were retrospectively reviewed for required information. The quantitative measurement of metals was conducted using atomic absorption spectroscopy, while screening of neurodevelopment was performed using the Ages and Stages Questionnaire. Modified Poisson regression and Bayesian kernel machine regression (BKMR) analyses were used to evaluate the prevalence ratio (PR) of their independent and joint associations.

Results

662 (14.8%) children were found to have possib

SUBMITTER: Shen Y 

PROVIDER: S-EPMC12411239 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature