Pustular reaction in adult-onset immunodeficiency due to anti-interferon-gamma autoantibodies.

ABSTRACT:

Introduction

Cutaneous manifestations in adult-onset immunodeficiency (AOID) resulting from anti-interferon-gamma autoantibody (AIGA) are prevalent and can be classified into infective and reactive disorders. To date, no clinical studies have specifically examined pustular reaction in patients with AOID. This study aimed to provide an original characterization of the clinical manifestations associated with pustular reaction in AOID and to compare these features with those observed in a clinically similar entity, generalized pustular psoriasis (GPP).

Methods

A retrospective study was conducted between January 2014 and June 2023 at the dermatology clinics of Maharaj Nakorn Chiang Mai Hospital, Chiang Mai and Srinagarind Hospital, Khon Kaen, Thailand. The study included adult p

SUBMITTER: Julanon N 

PROVIDER: S-EPMC12411423 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature