Assessing TDApp: An AI-based clinical decision support system for ADHD treatment recommendations.

ABSTRACT:

Introduction

Clinical practice guidelines (CPGs) have several limitations, namely: obsolescence, lack of personalization, and insufficient patient participation. These factors may contribute to suboptimal treatment recommendation compliance and poorer clinical outcomes. APPRAISE-RS is an adaptation of the GRADE heuristic designed to generate CPG-like treatment recommendations that are automated, updated, personalized, participatory, and explanatory using a symbolic AI approach. TDApp is a clinical decision support system (CDSS) that implements APPRAISE-RS for ADHD.

Methods

Two clinical trials were conducted. In both studies a total of 33 and 32 ADHD patients, respectively, requiring treatment initiation or a major treatment change were enrolled. TDApp recommendations were co

SUBMITTER: Baykova E 

PROVIDER: S-EPMC12411474 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature