Rising burden of cancer and atrial fibrillation-related mortality among adults in the United States, 1999-2019.

ABSTRACT:

Background

Atrial fibrillation (AF) is the most common cardiac arrhythmia, whereas cancer remains the second leading cause of death in the United States. Both conditions share several risk factors and may compound mortality risk. However, national trends in AF and cancer-related mortality remain underexplored.

Objective

To assess trends in mortality related to AF and cancer among US adults from 1999 to 2019, using demographic and geographic stratifications.

Methods

Data were obtained from the CDC WONDER Multiple Cause of Death data set. We identified individuals aged 25 years and older with AF (I48) and cancer (C00-C97) as an underlying or contributing cause of death. Age-adjusted mortality rates (AAMRs) per 100,000 population, average annual percentage change, and an

SUBMITTER: Saad M 

PROVIDER: S-EPMC12411967 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature