Engineering Motile Coacervate Droplets via Nanomotor Stabilization.

ABSTRACT: Coacervate-based artificial cells have gained significant attraction in synthetic biology for their ability to mimic life-like functions such as compartmentalization, selective molecular uptake, and the hosting of biochemical reactions. However, the incorporation of motility, a key feature of natural cells, remains underexplored. This is mainly caused by the dynamic character of coacervates, which hampers their stability and limits control over functional motile components within the structure. In this contribution, we have been able to address this gap by physically anchoring gold nanoparticles (AuNPs)-coated nanomotors at the coacervate interface in combination with a terpolymer membrane. The positively charged coacervates promoted the assembly of negatively charged nanomotors on their s

SUBMITTER: Sun S 

PROVIDER: S-EPMC12412170 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature