Association Between Preserved Glaucoma Eye Drops Exposure and Glaucoma Surgery Occurrence: A Nationwide 10-Year Outcome Study.

ABSTRACT:

Introduction

Preserved eye drops induce ocular toxicity, which may impair the management of glaucoma. This study aimed at assessing the association between the level of exposure to preserved glaucoma eye drops and the occurrence of glaucoma surgery.

Methods

This retrospective population-based cohort study included all patients ≥ 18 years old with a first glaucoma eye drops claim in the French national health insurance database between 1 January 2009 and 31 December 2017. A look-back period of 3 years before inclusion was used to select incident cases. Included patients were followed up until 31 December 2018. Patients were grouped according to the level of preservative exposure during follow-up: 0% (only preservative-free [PF] eye drops), "low-mixed" (both preserved and PF e

SUBMITTER: Chamard C 

PROVIDER: S-EPMC12413382 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature