Corneal transplantation wound dehiscence after penetrating keratoplasty and deep anterior lamellar keratoplasty.

ABSTRACT:

Purpose

To study clinical characteristics and outcomes of penetrating keratoplasty (PK) and deep anterior lamellar keratoplasty (DALK) wound dehiscence.

Methods

This retrospective case series assessed PK and DALK recipients with wound dehiscence at a single institution. We evaluated relationships between dehiscence etiologies, transplant indications, ocular/systemic comorbidities, keratoplasty type, and adverse post-dehiscence outcomes, especially graft failure and visual loss.

Results

Wound dehiscence occurred in 97/1019 eyes (90/863 PK [10.4%] vs 7/156 DALK [4.5%]; p = 0.002). Median time to dehiscence was 6.6 months (range = 1 day-39.2 years). Primary causes included trauma (44.1%) and ulceration (36.1%). Leading surgical indications associated with dehiscence were

SUBMITTER: Sarin SR 

PROVIDER: S-EPMC12413426 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature