Language Functional Connectivity Alterations During Resting State in Brain Arteriovenous Malformation Patients.

ABSTRACT:

Objectives

Unruptured brain arteriovenous malformations (AVMs) typically do not cause aphasia, even when the traditional language areas are affected by the nidus. We attempted to elucidate its language reorganization mechanism by analyzing the alterations in functional connectivity using functional connectivity (FC) and track-weighted static functional connectivity (TW-sFC) approaches.

Methods

This cross-sectional study prospectively enrolled patients with AVMs involving left-hemisphere language areas and healthy controls. All participants underwent resting-state functional magnetic resonance imaging (rs-fMRI) and diffusion tensor imaging scans. Conventional FC analysis was used to investigate the spatially segregated functional connectivity in the gray matter, and the TW-sF

SUBMITTER: Deng X 

PROVIDER: S-EPMC12413485 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature