Home-based dim light melatonin onset assessment among adults with obesity: feasibility and procedural considerations.

ABSTRACT:

Study objectives

Dim light melatonin onset (DLMO) is the best-established marker of central circadian phase and may contribute to unraveling the role of the circadian system in obesity. This study evaluated DLMO among individuals with obesity using a home-based assessment and explored its clinical correlates and procedural variations.

Method

Fifty-eight women (mean [SD] age 40.9 [7.8] years) and body mass index (41.4 [6.6] kg/m²) completed a home-based DLMO assessment, measures of sleep quality, diurnal preference, and cardiometabolic parameters. Procedural variations we explored included individualized versus standardized DLMO thresholds, 7 versus 3 days assessment of sleep onset timing (SOT), as well as diary-based, actigraphy-based, or a "combined" method to ca

SUBMITTER: Romo-Nava F 

PROVIDER: S-EPMC12413864 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature