Colorectal Cancer Incidence After Colonoscopy at Ages 45-49 or 50-54 Years.

ABSTRACT:

Background & aims

Colorectal cancer (CRC) incidence at ages younger than 50 years is increasing, leading to proposals to lower the CRC screening initiation age to 45 years. Data on the effectiveness of CRC screening at ages 45-49 years are lacking.

Methods

We studied the association between undergoing colonoscopy at ages 45-49 or 50-54 years and CRC incidence in a retrospective population-based cohort study using Florida's linked Healthcare Cost and Utilization Project databases with mandated reporting from 2005 to 2017 and Cox models extended for time-varying exposure.

Results

Among 195,600 persons with and 2.6 million without exposure to colonoscopy at ages 45-49 years, 276 and 4844 developed CRC, resulting in CRC incidence rates of 20.8 (95% CI, 18.5-23.4) and 30.6

SUBMITTER: Sehgal M 

PROVIDER: S-EPMC12413891 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature