Biomarkers for colorectal cancer detection: An insight into colorectal cancer and FDA-approved biomarkers.

ABSTRACT: Colorectal cancer (CRC) constitutes a significant global health challenge, accounting for a considerable proportion of cancer cases and associated mortality. Projections indicate a potential increase in new cases by 2040, attributed to demographic factors such as aging and population growth. Although advancements in the understanding of CRC pathophysiology have broadened treatment options, challenges such as drug resistance and adverse effects persist, highlighting the necessity for enhanced diagnostic methodologies. Timely detection markedly improves survival rates; however, colonoscopy, regarded as the gold standard for CRC screening, is constrained by its invasiveness and reliance on practitioner expertise. Consequently, the development of novel diagnostic approaches is imperative. Canc

SUBMITTER: Zamanian MY 

PROVIDER: S-EPMC12413984 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature