The treatment of cervical intraepithelial neoplasia grade 2 (HSIL): between active surveillance and surgery-a 10-year monocentric data analysis.

ABSTRACT:

Purpose

In recent years, active surveillance has been introduced as an alternative to excisional treatment in younger women with cervical intraepithelial neoplasia grade 2 (CIN 2) because spontaneous regression rate is high and excisional treatment is associated with an increased risk of preterm birth. However, the potential effect of this conservative approach on the risk of developing cervical cancer has not been evaluated very well.

Methods

The present study offers a real-life analysis of treatment pathways for patients diagnosed with CIN 2.

Results

Following CIN 2 diagnosis, 84 cases out of 187 (44.9%) were managed conservatively for at least 7 months and 103 cases (55.1%) were admitted for an excisional procedure LEEP (loop electrosurgical excision procedure). Ou

SUBMITTER: Ehlers U 

PROVIDER: S-EPMC12414026 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature