Haemodynamic characteristics of thin-walled regions in intracranial aneurysms: intraoperative imaging and CFD analysis.

ABSTRACT:

Background

Identifying haemodynamic factors associated with thin-walled regions (TWRs) of intracranial aneurysms is critical for improving pre-surgical rupture risk assessment. Intraoperatively, these regions are visually distinguished by a red, translucent appearance and are considered highly rupture prone. However, current imaging modalities lack the resolution to detect such vulnerable areas preoperatively. This study aimed to determine whether thin-walled regions exhibit distinct local haemodynamic profiles compared to adjacent normal-appearing wall regions.

Methods

Sixteen patient-specific models of unruptured middle cerebral artery aneurysms were reconstructed from digital subtraction angiography images. Intraoperative TWRs were identified using a colour segmentation m

SUBMITTER: Anbananthan H 

PROVIDER: S-EPMC12414043 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature