Predictors of progression from pre-frailty to frailty in older people: a systematic review and meta-analysis protocol.

ABSTRACT:

Introduction

Frailty is a global health issue, particularly among older adults, and is strongly associated with adverse health outcomes. The intermediate stage of pre-frailty, which represents a transition from robust health to frailty, has garnered growing concern due to its potential reversibility. This systematic review and meta-analysis will aim to identify predictors associated with the progression from pre-frailty to frailty in older adults.

Methods and analysis

A comprehensive literature search will be conducted in PubMed, Web of Science, Embase, Cochrane Library, CINAHL, PsycINFO, CNKI, Wanfang Database, China Science and Technology Journal Database, and China Biomedical Literature Database from inception to the most recent search date. Eligible studies will report p

SUBMITTER: Zhou FY 

PROVIDER: S-EPMC12414157 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature