Clinical outcome of advanced or recurrent endometrial carcinoma treated with chemotherapy: a French observational retrospective cohort: the ENDOVIE study.

ABSTRACT:

Objective

Advanced or recurrent endometrial carcinoma (EC) represents a significant clinical challenge. This study aimed to evaluate patient (age and comorbidities) and disease (histological subtypes and stages) characteristics, treatment patterns and survival outcomes in a real-world French healthcare setting.

Methods and analysis

In this national, multi-centre, retrospective observational cohort study, 200 patients with advanced or recurrent EC receiving first- or second-line chemotherapy during the year 2019 were analysed. Data collected included baseline characteristics, treatment regimens, real-world progression-free survival (rwPFS) and overall survival (OS).

Results

127 and 73 were included in the first and second lines, respectively. Endometrioid carcinoma was

SUBMITTER: Alexandre J 

PROVIDER: S-EPMC12414171 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature