Developing and validating a bi-polar gated respiratory motion management strategy for improved lung stereotactic body radiotherapy treatment.

ABSTRACT:

Background

Stereotactic body radiotherapy (SBRT) is an effective treatment for early-stage non-small cell lung cancer. However, patient breathing can affect treatment accuracy. Therefore, this study aimed to develop a bi-polar (BP) gated motion management strategy for SBRT and evaluate its feasibility geometrically and dosimetrically.

Methods

The BP strategy involved instructing patients to hold their breath briefly at the end of both inhalation (EI) and exhalation (EE), with radiation delivered only during these breath-holding periods. Eight volunteers were included to evaluate breathing stability, repeatability, and patient comfort. Additionally, 15 patients were retrospectively studied to evaluate the geometric and dosimetric efficiency of BP in intensity-modulated radiat

SUBMITTER: Li Z 

PROVIDER: S-EPMC12414274 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature