COVID-19 vaccination and use of antibiotics in COVID-19 patients: a systematic review and meta-analysis.

ABSTRACT:

Background

Vaccinations are considered one of the most effective medical interventions. Among other benefits, certain vaccinations help reduce antimicrobial resistance by decreasing antibiotic use. Considering reports of increased antimicrobial resistance during the COVID-19 pandemic, this study aimed to explore the relationship between COVID-19 vaccination status and antibiotic use in COVID-19 patients.

Methods

A systematic literature search was conducted in PubMed, Scopus, Web of Science, Embase, and Google Scholar between January 1, 2021, and November 6, 2024. The included studies were assessed for risk of bias using the Newcastle-Ottawa tool. Narrative synthesis and random-effects meta-analysis were employed to synthesize the evidence.

Results

Eight studies were i

SUBMITTER: Politis M 

PROVIDER: S-EPMC12414285 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature