Expanded Physiological Testing of the Lower Urinary Tract in Asymptomatic Women and Those With Urgency Urinary Incontinence: Findings From the LURN-Organ Study.

ABSTRACT:

Purpose

To investigate sensory and motor function of the bladder and urethra in women with and without urgency urinary incontinence (UUI).

Materials and methods

Treatment-seeking women with UUI and healthy, asymptomatic, nontreatment seeking controls enrolled in the Symptoms of Lower Urinary Tract Dysfunction Research Network Organ-Based study (LURN-Organ) and underwent a single session of physiological testing. Testing included rapid-fill cystometry before and after lidocaine administration, urethral pressure profiles, pelvic floor contraction (Kegel) testing, and tuning fork sensation testing at the urethral meatus.

Results

Data were collected from 31 asymptomatic controls and 56 women with UUI. Women with UUI were more likely to demonstrate detrusor overactivity (D

SUBMITTER: Hokanson JA 

PROVIDER: S-EPMC12414437 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature