Diagnosing abdominal neoplasms using a T2 mapping radial turbo spin-echo technique with partial volume correction.

ABSTRACT:

Objective

T2 mapping allows for the classification of focal liver lesions, differentiating malignancies from the most common benign liver lesions, hemangiomas, and bile duct hamartomas (BDH). Partial volume (PV) due to the presence of liver and lesion within the same voxel confounds the classification of small lesions. Our objective is to develop a robust two-component T2 estimation technique (SEPG2-SP) to enable accurate T2 estimation in the presence of PV.

Materials and methods

T2 estimation accuracy was evaluated using computer simulations, physical phantom data, and in vivo in 27 subjects with focal liver lesions (16 males, 62.4 ± 14.3 years old; 11 females, 66.8 ± 5.8 years old) imaged at 1.5 T with a radial turbo spin-echo (RADTSE) technique. The SEPG2-SP model was com

SUBMITTER: Keerthivasan MB 

PROVIDER: S-EPMC12414507 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature