Optimizing Workflow for Cone Beam Computed Tomography-Based Online Adaptive Radiation Therapy Toward Reduced Physician Involvement.

ABSTRACT:

Purpose

To evaluate the impact of an optimized online adaptive radiation therapy workflow on physician involvement.

Methods and materials

Data from a prospective phase 2 trial involving 34 prostate cancer patients treated with cone beam computed tomography (CBCT)-based online adaptive radiation therapy (62 Gy in 20 fractions) were analyzed. Manual interventions were required for 2 steps in the workflow: radiation therapy technologist review and adjustment of automatically segmented organs, guiding target segmentation, so-called "influencer," while physicians reviewed and refined the targets. Three different workflows were compared: 2-influencer (rectum and bladder), 3-influencer (+prostate), and 5-influencer (+seminal vesicles and bowel). Time for workflow steps, extent of m

SUBMITTER: Kalinauskaite G 

PROVIDER: S-EPMC12414823 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature