The feature and significance of lower limb MRI in adult myositis patients with anti-NXP2 antibody: a retrospective cohort study in China.

ABSTRACT:

Objective

This study aimed to describe the MRI features of lower limbs (thighs and calves) in patients with anti-NXP2 antibody positive myositis, and explore their relationship with clinical manifestations and prognosis.

Methods

Adult patients with anti-NXP2 antibody who underwent both thigh and calf MRI examinations simultaneously were enrolled between 2017 and 2023. The MRI features and medical records of patients were reviewed. Statistical analysis was conducted by SPSS 21.0.

Results

A total of 48 patients (29 females and 19 males) were included in the study. There were fifteen and seven patients with subcutaneous edema on the thigh and calf MRI, respectively. The incidence of fascia edema in the thigh was higher than that in the calf (50.0% vs. 22.9%, p = 0

SUBMITTER: Shanshan L 

PROVIDER: S-EPMC12414990 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature