Hubs, influencers, and communities of executive functions: a task-based fMRI graph analysis.

ABSTRACT:

Introduction

This study investigates four subdomains of executive functioning-initiation, cognitive inhibition, mental shifting, and working memory-using task-based functional magnetic resonance imaging (fMRI) data and graph analysis.

Methods

We used healthy adults' functional magnetic resonance imaging (fMRI) data to construct brain connectomes and network graphs for each task and analyzed global and node-level graph metrics.

Results

The bilateral precuneus and right medial prefrontal cortex emerged as pivotal hubs and influencers, emphasizing their crucial regulatory role in all four subdomains of executive function. Furthermore, distinct hubs and influencers were identified in cognitive inhibition and mental shifting tasks, elucidating unique network dynamics. Our

SUBMITTER: Davis AT 

PROVIDER: S-EPMC12415012 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature