Long COVID-19 alters muscle architecture and muscle-tendon force transmission: a one-year longitudinal study.

ABSTRACT:

Introduction

There are limited studies on the long-term effects of COVID-19 on skeletal muscle morphology and architecture. Therefore, this study aims to address this gap by assessing the effects of prior COVID-19 infection on quadriceps muscle architecture and tendon-aponeurosis complex (TAC) properties over a one-year period, comparing three cohorts: individuals with moderate COVID-19, individuals with severe COVID-19, and a healthy control group.

Methods

Seventy participants were included in the study and allocated to three groups: moderate COVID-19 (n = 22), severe COVID-19 (n = 18), and control (n = 30). Four assessments were conducted over 1 year for the COVID groups. Maximal voluntary isometric (MVIC) knee extension contractions were performed on an isometric dynamome

SUBMITTER: Ferreira LGJ 

PROVIDER: S-EPMC12415051 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature