Left ventricular unloading in patients with cardiogenic shock treated with veno-arterial extracorporeal membrane oxygenation.

ABSTRACT:

Aims

Cardiogenic shock remains a significant cause of mortality despite multiple advancements in medical interventions. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) provides crucial circulatory support but also increases left ventricular (LV) after-load, potentially worsening outcomes. Effective LV unloading strategies can enhance patient survival during VA-ECMO treatment. Our aim was to evaluate the impact of LV unloading strategies, including intra-aortic balloon pump (IABP) and Impella, on outcomes such as mortality and adverse effects in patients with cardiogenic shock treated with VA-ECMO.

Methods and results

A systematic search of EMBASE and Medline was conducted from inception up to 20 August 2024. Additional sources included forward citation searches o

SUBMITTER: Dar BY 

PROVIDER: S-EPMC12415181 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature