Altered Reward Processing in Obsessive-Compulsive Disorder: Insights From Active and Observational Learning.

ABSTRACT: Obsessive-compulsive disorder (OCD) has been associated with altered performance monitoring, reflected in enhanced amplitudes of the error-related negativity in the event-related potential. However, this is not specific to OCD, as overactive error processing is also evident in anxiety. Although similar neural mechanisms have been proposed for error and feedback processing, it remains unclear whether the processing of errors as indexed by external feedback, reflected in the feedback-related negativity (FRN), is altered in OCD. Likewise, it is currently unknown whether performance monitoring in OCD differs between learning from self-performed and observed outcomes. The present study compared OCD patients (n = 27) with healthy controls (HCs; n = 27) and patients with social anxiety disorder (

SUBMITTER: Vahedi J 

PROVIDER: S-EPMC12415511 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature