Characterization of <i>Streptococcus mitis</i> subsp. <i>carlssonii</i> isolated from human vagina: prevalence, phenotypic, and genomic insights.

ABSTRACT: The genus Streptococcus is a heterogenous group of commensal and pathogenic bacteria. Members of this genus are classified into two major groups, the pyogenic group and the viridans group streptococci (VGS). VGS are frequently found as normal members of the human microbiome and are regarded as commensals. In this work, we characterized a VGS strain isolated from the vaginal swab sample of a Korean patient diagnosed with endometrial cancer. Phylogenetic, phenotypic, and genome-based analyses confirmed the classification of the strain K0074 as a member of the S. mitis complex. Based on the phylogenetic analyses, the species belonged to the recently established Streptococcus mitis subsp. carlssonii. The strain was found to be rare in the vaginal microbiome, but pre

SUBMITTER: Montecillo JAV 

PROVIDER: S-EPMC12415561 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature