Transcriptomic Meta-Analysis Reveals Hub Genes Integrating Multiple Abiotic Stress Responses in Wheat.

ABSTRACT: Climatic challenges increasingly threaten global food security, necessitating crops with enhanced multi-stress resilience. Through systematic transcriptomic analysis of 100 wheat genotypes under heat, drought, cold, and salt stress, we identified 3237 differentially expressed genes (DEGs) enriched in key stress-response pathways. Core transcription factors (MYB, bHLH, HSF) and two functional modules governing abiotic tolerance were characterized. Phenotypic assessments revealed significant stress-induced alterations in plant height, biomass, and chlorophyll content. RT-qPCR confirmed marked upregulation of eight candidate genes, including BES1/BZR1 and GH14, across most stresses, indicating their critical role in wheat's adaptive responses. This st

SUBMITTER: Ding M 

PROVIDER: S-EPMC12415591 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature