Coagulation Disorders in Patients With Acute Respiratory Distress Syndrome Following Acute Aortic Dissection: A Prospective Observational Study.

ABSTRACT:

Background

Coagulation disorders are potentially one of the most important pathogeneses of acute respiratory distress syndrome (ARDS) following acute type A aortic dissection (ATAAD). This study aimed to determine whether aortic dissection singularly and cardiopulmonary bypass (CPB) surgery can activate coagulation pathways, promoting ARDS development in patients with ATAAD.

Methods

A total of 450 patients who received treatment at Beijing Anzhen Hospital, Capital Medical University, between March 2023 and February 2024 were consecutively enrolled in this prospective cohort study. We analyzed the clinical factors and measured serum coagulation biomarkers by enzyme-linked immunosorbent assay (ELISA) among patients with ATAAD, aortic aneurysm (AA), or unstable angina (UA). Log

SUBMITTER: Liu M 

PROVIDER: S-EPMC12415743 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature