Coordination sphere interactions drive isomer selection in heteroleptic Pd(ii) cages with low-symmetry ligands.

ABSTRACT: The targeted formation of low-symmetry coordination cages represents a significant design challenge but offers the potential to engineer bespoke molecular hosts with precision. In this work, we have combined the design principles of geometric complementarity and coordination sphere engineering to direct the site- and orientation-selective self-assembly of heteroleptic Pd₂L^A ₂L^B ₂-type coordination cages from low-symmetry ligands. The effects of different combinations of heterocyclic donors and their locations within the cage structures on isomer distributions were studied, providing insights on shifts in the balance between non-covalent interactions in the first and second coordination spheres of the cages. For cages with one low-symme

SUBMITTER: Molinska P 

PROVIDER: S-EPMC12415893 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature