Osteoporosis screening and major osteoporotic fracture prediction by cranial computed tomography-derived Hounsfield units: a multi-center study on opportunistic osteoporosis screening.

ABSTRACT:

Background

The incidence of osteoporosis and osteoporotic fragility fractures is increasing due to demographic changes. Therefore, early diagnosis is desirable in order to preserve bone health and prevent low-trauma fractures. Opportunistic screening for osteoporosis by frequently performed computed tomography scans could offer a potential solution. Cranial computed tomography is often performed in potential high-risk patients for osteoporosis due to frequent falls in older ages. The aim of this study was to examine the potential value of opportunistic osteoporosis screening by cranial computed tomography-derived Hounsfield units in the overall clinical context, including sustained major osteoporotic fractures, pre-existing diseases and lifestyle factors.

Materials and methods</

SUBMITTER: Wakolbinger-Habel R 

PROVIDER: S-EPMC12416018 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature