A prospective, multicenter study of invasive fungal disease caused by molds in children and adults in Chile.

ABSTRACT:

Background

Invasive mold diseases (IMDs) are a severe complication of immunocompromised subjects and an emerging problem among severely ill, apparently immunocompetent patients. The aim of this study was to describe the epidemiological and clinical features of IMDs in Chile.

Methods

Prospective study of IMD cases in children and adults from 11 reference hospitals in Chile from May 2019 to May 2021.

Results

One hundred seventy-six cases were included, 135 in adults and 41 in children, with an overall incidence of 0.4/1,000 admissions. The median age was 10.5 years in children and 56.6 years in adults, with male gender predominance in adults (61.5% versus 41.5%, p = 0.03). Immunosuppression was the most common condition in both children and adults. However, cancer, neut

SUBMITTER: Rabagliati R 

PROVIDER: S-EPMC12416711 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature