Global burden of head and neck cancer from 1990 to 2021: A comprehensive analysis and projections to 2030 based on the global burden of disease study 2021.

ABSTRACT:

Background

Head and neck cancer (HNC) is a significant global health concern with rising incidence and mortality in certain regions. This study aimed to evaluate the global burden and temporal trends of HNC from 1990 to 2021 and to project its future burden through 2030.

Methods

Data were obtained from the Global Burden of Disease (GBD) 2021 study. Joinpoint regression was used to assess temporal trends in age-standardized incidence rates (ASIR), age-standardized death rates (ASDR), and disability-adjusted life years (DALYs). Age-period-cohort (APC) and Bayesian APC (BAPC) models were applied to evaluate age, period, and cohort effects and to project future trends. Decomposition analysis was conducted to explore the contributions of population aging, growth, and epidemiologi

SUBMITTER: Deng M 

PROVIDER: S-EPMC12416713 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature