An Examination of Sex Differences and Cigarette Smoking as Predictors of COPD Prevalence and Incidence in Older US Adults.

ABSTRACT:

Introduction

This study examined the main and interactive effects of sex, cigarette smoking status, cigarette pack-years, and second-hand smoke exposure on COPD prevalence and incidence.

Methods

COPD prevalence was estimated for US adults aged 40+ years from Wave 1 of the Population Assessment of Tobacco and Health Study (n = 12 296). Incidence analyses included adults from the initial sample without a COPD diagnosis (n = 6611). Multivariable Poisson regressions assessed prevalence and incidence based on self-reported sex and cigarette smoking, adjusted for covariates.

Results

COPD prevalence was 7.4% and 9.4% and incident COPD was 5.0% and 8.7% for males and females, respectively. The adjusted prevalence ratio (aPR) for COPD for females was 1.26 [95% CI = 1.11, 1.44]

SUBMITTER: Ozga JE 

PROVIDER: S-EPMC12416757 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature