Association between dietary selenium intake and the prevalence of prediabetes in Newfoundland population: a cross-sectional study.

ABSTRACT:

Introduction

Emerging evidence highlights the role of selenium (Se) in glucose metabolism through selenoprotein-mediated antioxidant and anti-inflammatory pathways. However, population-specific data remains inconclusive. This study aims to investigate the association between dietary Se intake and prediabetes prevalence in Newfoundland, a population characterized by genetic homogeneity and high obesity rates (39.4%).

Methods

This cross-sectional study used data from 2,665 participants in the Complex Diseases in the Newfoundland Population: Environment and Genetics (CODING) study. Prediabetes was defined by the American Diabetes Association criteria for impaired fasting glucose (FPG: 5.6-6.9 mmol/L). Dietary Se intake was assessed using the Willett food frequency questionnaire

SUBMITTER: Yu S 

PROVIDER: S-EPMC12417185 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature